BcISLogo
Bio-chemical Infomatics Solutions
Lab Products and Services
Greek Version

Limulus Pyrotell Accessories Pyros Kinetix Flex Fungitell IVD Pyros Express

 Home   Company   Products   Partners   Certificates   Services   links   Contact 

reagents Reagents

Limulus Amebocyte Lysate (LAL) Test

Control Standard Endotocin (CSE)

They are economical endotoxin vials for use as standard in endotoxin testing. They replace RSE in an assay and they come with a certificate of analysys.

CSE Control Standard Endotocin (CSE)
Product Inserts pdf downloads:
CSE 0.5g/vial | CSE 125g/vial | CSE 10ng/vial
Product Info Sheet

Product Description

Control Standard Endotoxin (CSE) is a widely used standard for endotoxin testing. It is a purified extract of E. coli O113:H10, the same strain used for the United States Pharmacopeia and the European Pharmacopeia reference standard endotoxin (RSE).

CSE is used as an economic alternative to the RSE. CSEs are standardized against the RSE as indicated on the Certificate of Analysis, so that results can be reported in Endotoxin Units (EU) and International Units (IU). CSE can be used for all LAL testing. A 10 ng/vial CSE is made specifically for use with our Pyrochrome chromogenic reagent.

Test Performance

CSE is used to make standard curves and controls when performing the LAL assay. The concentrations used are dependent on the type of assay (e.g., chromogenic, gel-clot, or turbidimetric) and for photometric methods, the detection range required.

Product Stability

CSE is reconstituted with LRW or equivalent, and is stored at 2-8C before and after reconstitution. Once reconstituted, the maximum storage time for the different CSE preparations is listed below:
    10 ng/vial - - - - - - - - - - - - - - - - - - - - - - - - - -7 days
    0.5 g/vial - - - - - - - - - - - - - - - - - - - - - - - - 4 weeks
    125 g/vial - - - - - - - - - - - - - - - - - - - - - - - 3 months

CSE should not be frozen.

Product Reconstitution

CSE is reconstituted with LAL Reagent Water (LRW) (or equivalent). Please refer to the Certificate of Analysis when using CSE. A Certificate of Analysis exists for each CSE-lysate lot combination.

Product Packaging

The most commonly used size is 0.5 g/vial. The 0.5 g/vial is also used for testing depyrogenation ovens. The 125 g/vial is typically used for special purposes, e.g., making endotoxin challenge articles for validation of depyrogenation processes. The 10 ng/vial CSE is available in packs of five vials.


Control Standard Endotoxin (CSE)
#E0005 Escherichia coli O113:H10, 0.5 g/vial 1 Pack
#E0005-5 Escherichia coli O113:H10, 0.5 g/vial 5 Pack
#E0005-25 Escherichia coli O113:H10, 0.5 g/vial 25 Pack
#E0125 Escherichia coli O113:H10, 125 g/vial 1 Pac
#E0125-5 Escherichia coli O113:H10, 125 g/vial 5 Pack
#E0125-25 Escherichia coli O113:H10, 125 g/vial 25 Pack
#EC010 Escherichia coli O113:H10, 10 ng/vial, 5 vials per pack, for use with Pyrochrome kits 1 Pack
#EC010-5 Escherichia coli O113:H10, 10 ng/vial, 5 vials per pack, for use with Pyrochrome kits 5 Pack
#EC010-25 Escherichia coli O113:H10, 10 ng/vial, 5 vials per pack, for use with Pyrochrome kits 25 Pack



Designer: G. Pap
Hosted by: BcIS
limulus